Cartalax is the tripeptide Ala-Glu-Asp (AED), a bioregulator from the Russian peptide research program developed to support cartilage tissue and joint reserve. The mechanism operates at the level of chondrocytes—specialized cells maintaining cartilage structure. Cartalax interacts with DNA regulatory regions in these cells, normalizing expression of genes responsible for synthesis of extracellular matrix components. This applies primarily to type II collagen—the main structural protein of cartilage—and proteoglycans that provide elasticity and hydration.
In preclinical studies on models of degenerative cartilage change, Cartalax administration improved chondrocyte capacity to synthesize matrix components, reduced inflammatory signals within the joint environment, and mechanical properties of cartilage showed positive dynamics. This fundamentally differs from standard chondroprotectors that merely supply building material (glucosamine, chondroitin), whereas Cartalax addresses the problem at the cell-regulatory level—normalizing the work of cells responsible for cartilage maintenance.
Practically, Cartalax is considered in two scenarios: slowing age-related cartilage wear in osteoarthritis or chronic loading, and support in post-traumatic or post-operative joint rehabilitation. The evidence base remains predominantly preclinical and observational; large controlled trials in international literature are few, limiting confidence when extrapolating to humans.
🦴 Chondrocytes and matrix (regulation): ★★★★☆
🔧 Type II collagen and proteoglycans: ★★★★☆
⚙️ Osteoarthritis and age-related wear (preclinical): ★★★☆☆
✅ Safety: ★★★★☆ (favorable bioregulator profile)
⚠️ Possible sensations and side effects: usually neutral; little adverse-event data
🤝 Combinations (goal → stack)
🦴 Long-term joint reserve → Cartalax + (BPC-157 + TB-500)
🦴 Cartilage + matrix → Cartalax + GHK-Cu
🔧 Joints + anti-inflammatory background → Cartalax + BPC-157
| CAS number | 137525-51-0 |
| Batch purity | 99.20 % |
Full information in our guide
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